人(rén)才教育

張大(dà)生

中國科學院分(fēn)子植物(wù)科學卓越創新中心辰山科學研究中心

在崗研究生導師情況介紹

				姓　名	張大(dà)生
				研究組	觀賞植物(wù)資源及創新利用(yòng)研究組
				性　别	男(nán)
				專業名稱	分(fēn)子生物(wù)學
				技術職務	研究員(yuán)
				行政職務	-
				Mail地址	zhdash001@163.com
指導博士生總數	0	指導碩士生總數	3	通(tōng)訊地址	上海松江區(qū)辰花公路3888号上海辰山植物園/中科院上海辰山植物(wù)科學研究中心
目前博士生數	0	目前碩士生數	3	郵政編碼	201602
研究方向	觀賞植物(wù)基因工程
研究工作	（1）荷花花色素代謝途徑功能基因研究；（2）重瓣花的(de)發生機制；（3）荷花花粉遺傳發育研究。
獲獎情況	上海市“明(míng)治乳業生命科學獎”
指導研究生情況	2014-2015年在上海辰山植物園（中國科學院上海辰山植物(wù)科學研究中心）培養碩士研究生3名（均在讀）。
個(gè)人(rén)簡介	教育：本科：江蘇師範大(dà)學生命科學學院（學士，1996），研究生：福建農林(lín)大(dà)學園藝學院（碩士，2002）、上海交通(tōng)大(dà)學生命科學技術學院（博士，2010）。經曆：江蘇師範大(dà)學講師（1996-2005）；同濟大(dà)學心律失常教育部重點實驗室助理(lǐ)研究員(yuán)（2010-2013）；中國科學院上海辰山植物(wù)科學研究中心副研究員(yuán)，福建農林(lín)大(dà)學專碩校外指導老師（2014-至今）。
近期三年（代表性）論著	1. Lijie Cui, Fenfen Huang, Dasheng Zhang, Pan Liao, Yuping Lin, Jie Zong, Guoyin Kai. Transcriptome exploration for further understanding of the tropane alkaloids biosynthesis in Anisodus acutangulus. Molecular Genetics and Genomics, 2015, DOI: 10.1007/s00438-015-1005-y 2. Lijie Cui, Xiaoling Ni, Qian Ji, Xiaojuan Teng, Yanrui Yang, Chao Wu, David Zekria, Dasheng Zhang,* Guoyin Kai . Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila. Scientific Reports, 2015, 5, 8227; DOI:10.1038/srep08227. 3. Weiwei Zhang, Daike Tian, Xiu Huang, Yuxian Xu, Haibo Mo, Yanbo Liu, Jing Meng, Dasheng Zhang. Characterization of Flower-Bud Transcriptome and Development of Genic SSR Markers in Asian Lotus (Nelumbo nucifera Gaertn.), PLOS ONE, 2014, 9 (11), e112223. 4. Jun Li, Changming Li, Dasheng Zhang,* et al., SNX13 reduction mediates heart failure through degradative sorting of apoptosis repressor with caspase recruitment domain, Nature Communication, 2014, Oct 8;5:5177. doi: 10.1038/ncomms6177. 5. Jun Li, Man Qi, Changming Li, Dan Shi, Dasheng Zhang, et al., Tom70 serves as a molecular switch to determine pathological cardiac hypertrophy, *Cell Research, 2014, 24, 977-993, doi:10.1038/cr.2014.94 6. J Li, DS Zhang (Co-first Author), JC Ye, et al. Dynamin-2 mediates heart failure by modulating Ca2+-dependent cardiomyocyte apoptosis. International Journal of Cardiology, 2013, Oct 3;168(3):2109-2119. 7. J Li, L Xu, JC Ye, X Li, DS Zhang, et al. Aberrant dynamin 2-dependent Na+/H+ exchanger-1 trafficking contributes to cardiomyocyte apoptosis, Journal of Cellular and Molecular Medicine. 2013, Sep;17(9):1119-1127. 8. Junjie Xiao, Dandan Liang, Hong Zhang, Ying Liu, Dasheng Zhang, et al. MicroRNA-204 is required for differentiation of human-derived cardiomyocyte progenitor cells, Journal of Molecular and Cellular Cardiology, 2012, 53: 751–759. 9. Congmao Wang, Jie Xu, Dasheng Zhang, et al; An effective approach for identification of in vivo protein–DNA binding sites from paired-end ChIP-Seq data. BMC Bioinformatics, 2010, 11: 81. 10.* Jie Xu, Caiyun Yang, Zheng Yuan, Dasheng Zhang, et al. Regulatory Network of ABORTED MICROSPORES (AMS) Required for Postmeiotic Male Reproductive Development in Arabidopsis thaliana. *The Plant Cell, 2010, 22 (1): 91-107. 11. Dasheng Zhang, Wanqi Liang, Changsong Yin, et al; OsC6, encoding a lipid transfer protein (LTP), is required for postmeiotic anther development in rice. The Plant physiology, 2010, 154:149-162. 12.* Zhang Dasheng, Tan Hexin, and Zhang Dabing; Understanding the molecular mechanism of rice pollen development. 5th International Hybrid Rice Symposium.2008. 13. Da-Sheng Zhang, Wan-Qi Liang, Zheng Yuan, et al; Tapetum Degeneration Retardation is Critical for Aliphatic Metabolism and Gene Regulation during Rice Pollen Development. *Molecular Plant, 2008, 1 (4):599-610. 14.* Na Li, Da-Sheng Zhang (Co-first author), Hai-Sheng Liu, et al. The Rice Tapetum Degeneration Retardation Gene Is Required for Tapetum Degradation and Anther Development, *The Plant Cell*, 2006, 18, 2999–3014.